ペプチド合成受託サービス修飾一覧と参考料金

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カスタムペプチド合成受託サービスの末端修飾や蛍光色素標識などの修飾と料金の一覧ですが、こちらに記載がない場合もお気軽にお問い合わせください。

ペプチド合成受託サービスのさまざまな修飾

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N末端修飾

20mg以上も可能ですのでお問い合わせ下さい。記載の金額は参考料金です。

Item AN末端修飾1-9 mg10-19 mg
A0{H-},Free amino group00
A1{Ac},Acetylation00
A2-BrC2{Br-Ac},Bromoacetyl8,00010,000
A2-BrC3{Bromopropionyl}8,00010,000
A2-ClC2{Cl-Ac},Chloroacetyl8,00010,000
A3{Fmoc},9-Fluorenylmethyloxycarbonyl00
A4{Z},{CBZ},Benzyloxycarbonyl00
A5{Bz},benzoyl00
A6{Boc},tertbutoxycarbonyl18,00019,000
A7{Suc},succinyl2,0002,000
A8{Allyl},allyl18,00019,000
A9{Acryl},acryl18,00019,000
A10{Alloc},allyloxycarbonyl18,00019,000
A11{For}, Formylation5,0006,000
A12{HPP},4-Hydroxyphenylpropionic acid5,0006,000
A13{pGlu},{Pyr},Pyroglutamyl3,0004,000
A14{LA}, Lipoic acid5,0006,000
A15-C3{Mpa},3-Mercaptopropyl5,0006,000
A15-C6{6-mercaptohexanoic acid}18,00019,000
A16{Mal}, Maleimide, Maleoyl-b-Ala64,00070,000
A17{MTX}, Methotrexate18,00019,000
A18{PEG1900}, PEG1900-NH-18,00019,000
A19-2K-NH2{NH2-PEG2000}, NH2-PEG2000-NH-18,00019,000
A19-2K-Ome{mPEG2000}, MeO-PEG2000-NH-18,00019,000
A19-3K-Ome{mPEG3000}, MeO-PEG3000-NH-18,00019,000
A19-5K-Ome{mPEG5000}, MeO-PEG5000-NH-18,00019,000
A20{SATA}, S-acetylthioacetate18,00019,000
A21{SATP}, S-acetylthiopropionate18,00019,000
A22{Cholesteryl-}, Cholesteryl chloroformate18,00019,000
A23{Glucose-}34,00035,000
A24Pyridin-1-yl-Acetyl-39,00044,000
A254-Dimethylamino-Pyridin-1-yl-39,00044,000
A26Adamantanecarbonyl-39,00044,000

N末端Fatylation

Item BN末端Fatylation1-9 mg10-19 mg
B1{But}, Butyric acid   C48,00010,000
B2{Hex}, Hexanoic acid   C68,00010,000
B3{Oct}, Octanoic acid   C88,00010,000
B3F{F-Oct}, Perfluoro Octanoic acid   F15C826,00028,000
B4{Dec}, Decanoic acid   C108,00010,000
B4F{F-Dec}, Perfluoro Decanoic acid   F19C1026,00028,000
B5{Lau}, Lauric acid   C128,00010,000
B5F{F-Lau}, Perfluoro Lauric acid    F23C1226,00028,000
B6{Myr}, Myristic acid   C148,00010,000
B6F{F-Myr}, Perfluoro Myristic acid   F27C1426,00028,000
B7{Pal}, Palmitic acid  C168,00010,000
B8{Ste}, Stearic acid   C188,00010,000
B10{Pam3C}, Tripalmitoyl cysteine, {Pal-Cys(Pal)2-}52,00055,000

C末端修飾

Item CC末端修飾1-9 mg10-19 mg
C0{-OH}, free acid group00
C1{NH2}, Amidation00
C2{-CHO}, peptide aldehydes74,00081,000
C3{-ol}, alcohol peptide34,00035,000
C4{CMK}, chloromethylketone74,00081,000
C5{FMK}, Fluoromethylketone74,00081,000
C6{Cya}, Cysteamide34,00035,000
C7{pNA},p-nitroaniline26,00028,000
C8{-pNP}, para-nitrophenol34,00035,000
C9{AMC},7-Amino-4-methylcoumarin34,00035,000
C10{AFC}44,00046,000
C11-OMe (C-terminal)16,00019,000
C12-OEt (C-terminal)16,00019,000
C13-OBzl (C-terminal)16,00019,000
C14-OtBu (C-terminal)34,00035,000
C15{-OSu}, hydroxysucinimide ester74,00081,000
C16-NHMe (C-terminal)26,00028,000
C17-NHEt (C-terminal)26,00028,000
C18-NHisopen (C-terminal)39,00044,000
C19 -NH(CH2)6 (C-terminal)39,00044,000
C20 -NHPh (C-terminal)26,00028,000
C21{NHEt(O)EtNH-Fmoc}, 2,2′-Oxydi Ethanamine-Fmoc34,00035,000
C22{NHEt(EtNH-Myr)2}39,00044,000
C23 -NH(OMe)Me (C-terminal)39,00044,000
C24-TBzl (C-terminal)34,00035,000
C25 -NHNH2 (C-terminal)26,00028,000
C26 -ED (C-terminal), -NH-CH2CH2-NH226,00028,000
C27 -BD (C-terminal), -NH-CH2CH2CH2CH2-NH226,00028,000

D-form normal amino acid

Item DD form normal amino acid1-9 mg10-19 mg
D1{D-Ala}3,0004,000
D2{D-Arg}8,00010,000
D3{D-Asp}5,0006,000
D4{D-Asn}5,0006,000
D5{D-Cys}5,0006,000
D6{D-Glu}5,0006,000
D7{D-Gln}6,0008,000
D8{D-His}5,0006,000
D9{D-Allo-Ile}6,0008,000
D10{D-Leu}3,0004,000
D11{D-Lys}5,0006,000
D12{D-Met}3,0004,000
D13{D-Pro}3,0004,000
D14{D-Phe}3,0004,000
D15{D-Ser}5,0006,000
D16{D-Tyr}5,0006,000
D17{D-Thr}5,0006,000
D18{D-Trp}8,00010,000
D19{D-Val}3,0004,000

Unusual amino acid

Item EUnusual amino acid1-9 mg10-19 mg
E1{Beta-Asp}5,0006,000
E2{D-Beta-Asp}6,0008,000
E3{Gamma-Glu}5,0006,000
E4{D-Gamma-Glu}6,0008,000
E5{Cys(Cam)}5,0006,000
E6{Cys(Acm)}5,0006,000
E7{Cys(tBu)}5,0006,000
E8{Met(O)}6,0008,000
E9{D-Met(O)}8,00010,000
E10{Met(O)2}6,0008,000
E11{D-Met(O)2}8,00010,000
E12{Lys(Ac)}5,0006,000
E13{Ac-Lys}6,0008,000
E14{Lys(Dde)}23,00027,000
E15{Lys(Alloc)}15,00017,000
E16{Ser(octanoic acid)}36,00039,000
E17{D-Ser(octanoic acid)}36,00039,000
E18{Aib}5,0006,000
E19{Abu}5,0006,000
E20{D-Abu}5,0006,000
E21{Hyp}3,0004,000
E22{Phg}3,0004,000
E23{D-Phg}3,0004,000
E24{Nva}5,0006,000
E25{D-Nva}5,0006,000
E26{Nle}5,0006,000
E27{D-Nle}5,0006,000
E28{Cit}5,0006,000
E29{D-Cit}6,0008,000
E30{Orn}5,0006,000
E31{D-Orn}6,0008,000
E32{Pen}10,00012,000
E33{D-Pen}5,0006,000
E34{Cpg}, cyclopentylglycine6,0008,000
E35{Cha}5,0006,000
E36{D-Cha}5,0006,000
E37{Chg}5,0006,000
E38{D-Chg}5,0006,000
E39{Dab}6,0008,000
E40{Dap}6,0008,000
E41{Pra}6,0008,000
E42{D-Pra}6,0008,000
E43{Gly(allyl)}6,0008,000
E44{D-Gly(allyl)}6,0008,000
E45{D-1-Nal}5,0006,000
E46{L-1-Nal}5,0006,000
E47{D-2-Nal}5,0006,000
E48{L-2-Nal}5,0006,000
E49{D-2-Pal}5,0006,000
E50{L-2-Pal}5,0006,000
E51{D-3-Pal}5,0006,000
E52{L-3-Pal}5,0006,000
E53{D-4-Pal}5,0006,000
E54{L-4-Pal}5,0006,000
E55{Cys(pMeBzl)}5,0006,000
E56{Cys(pMeOBzl)}5,0006,000
E57{Oic}6,0008,000
E58{Tic}6,0008,000
E59{Cys(Bzl)}5,0006,000
E60{Epsilon-Lys}5,0006,000
E61{D-Epsilon-Lys}6,0008,000
E62{5-ASA}18,00019,000
E63{Bpa}18,00019,000
E64{Pip}6,0008,000
E65{Nip}8,00010,000
E66{2-Aze}8,00010,000
E67{3-Aze}10,00012,000
E68[Psi(CH2NH)]126,000136,000
E69[CS-NH]126,000136,000
E70{Lys(propionyl)}15,00016,000
E71{Lys(Butanoyl)}15,00016,000
E72{Lys(propargyl)}15,00016,000
E73{X}, 20 Kinds mixture amino acids5,0006,000
E74{isoGln}10,00012,000
E75{D-isoGln}15,00016,000
E76Cys(Mal-PEG2000)63,00068,000
E77{Ser(O-b-D-Glc)}126,000136,000
E78{Thr(O-b-D-Glc)}126,000136,000
E79{Tyr(O-b-D-Glc)}126,000136,000

Fluorescence/Dye Labeling

Item FFluorescence/Dye Labeling1-9 mg10-19 mg
F1Biotin (N-Terminal)5,0006,000
F1LBiotin-LC (N-Terminal)5,0006,000
F1KLys(Biotin) (middle)31,00033,000
F1KCLys(Biotin) (C temrinus)31,00033,000
F1KNLys(Biotin) (N terminus)15,00016,000
F1EDEDBiotin (C terminus)39,00043,000
F2LFITC-LC (N-Terminal)18,00019,000
F2KLys(FITC) (middle)39,00043,000
F2KCLys(FITC) (C temrinus)39,00043,000
F2KNLys(FITC) (N terminus)19,00021,000
F2EDEDFITC (C temrinus)46,00051,000
F35-FAM (N-Terminal)18,00019,000
F3L5-FAM-LC (N-Terminal)18,00019,000
F3KLys(5-FAM) (middle)39,00043,000
F3KCLys(5-FAM) (C temrinus)39,00043,000
F3KNLys(5-FAM) (N-Terminus)19,00021,000
F3EDED5-FAM (C temrinus)46,00051,000
F4Dansyl (N-Terminal)18,00019,000
F4LDansyl-LC (N-Terminal)18,00019,000
F4KLys(Dansyl) (middle)39,00043,000
F4KCLys(Dansyl) (C temrinus)39,00043,000
F4KNLys(Dansyl) (N-Terminus)19,00021,000
F4EDEDDansyl (C temrinus)46,00051,000
F5TAMRA (N-Terminal)37,00039,000
F5LTAMRA-LC (N-Terminal)37,00039,000
F5KLys(TAMRA) (middle)63,00068,000
F5KCLys(TAMRA) (C temrinus)63,00068,000
F5KNLys(TAMRA) (N-terminus)32,00034,000
F5EDEDTAMRA (C temrinus)76,00081,000
F6Lys(Dnp) (middle)15,00017,000
F6-DD-Lys(Dnp) (middle)31,00035,000
F6-DabDab(Dnp) (middle)31,00035,000
F6-DapDap(Dnp) (middle)31,00035,000
F6-EDEDDnp (C terminus)46,00051,000
F7MCA (N-Terminal)18,00019,000
F7KLys(MCA) (middle)63,00068,000
F7KCLys(MCA) (C temrinus)63,00068,000
F7KNLys(MCA) (N-terminus)32,00034,000
F83-Indolylacetic acid (N-Terminal)5,0006,000
F9Cys(Npys) (N-terminus)15,00017,000
F10PyBA- (N-Terminal), 1-pyrenebutyric acid18,00019,000
F11Fa- (N-Terminal), 3-[2-2furyl]acrylic acid18,00019,000
F12Rhodamine B- (N-Terminal)18,00019,000
F13D-Luciferin (N-terminus)68,00077,000
F14Cy3- (N-Terminal)68,00077,000

Phe/Tyr Analogs amino acid

Item GPhe/Tyr Analogs amino acid1-9 mg10-19 mg
G1{D-2-Cl-Phe}6,0008,000
G2{L-2-Cl-Phe}6,0008,000
G3{D-3-Cl-Phe}6,0008,000
G4{L-3-Cl-Phe}6,0008,000
G5{D-4-Cl-Phe}5,0006,000
G6{L-4-Cl-Phe}5,0006,000
G7{D-3,4-DiCl-Phe}8,00010,000
G8{L-3,4-DiCl-Phe}8,00010,000
G9{D-4-Br-Phe}5,0006,000
G10{L-4-Br-Phe}5,0006,000
G11{D-3-F-Phe}6,0008,000
G12{L-3-F-Phe}6,0008,000
G13{D-4-F-Phe}5,0006,000
G14{L-4-F-Phe}5,0006,000
G15{D-4-NO2-Phe}5,0006,000
G16{L-4-NO2-Phe}5,0006,000
G17{D-4-I-Phe}5,0006,000
G18{L-4-I-Phe}5,0006,000
G19{D-3-CN-Phe}6,0008,000
G20{L-3-CN-Phe}6,0008,000
G21{D-4-CN-Phe}5,0006,000
G22{L-4-CN-Phe}5,0006,000
G23{D-2-Me-Phe}6,0008,000
G24{L-2-Me-Phe}6,0008,000
G25{D-4-Me-Phe}5,0006,000
G26{L-4-Me-Phe}5,0006,000
G27{D-4-NH2-Phe}8,00010,000
G28{L-4-NH2-Phe}8,00010,000
G29{D-3-Cl-Tyr}8,00010,000
G30{L-3-Cl-Tyr}5,0006,000
G31{D-3,5-DiCl-Tyr}8,00010,000
G32{L-3,5-DiCl-Tyr}8,00010,000
G33{D-3,5-DiBr-Tyr}8,00010,000
G34{L-3,5-DiBr-Tyr}8,00010,000
G35{D-3-I-Tyr}8,00010,000
G36{L-3-I-Tyr}8,00010,000
G37{D-3,5-DiI-Tyr}8,00010,000
G38{L-3,5-DiI-Tyr}8,00010,000
G39{D-3-NO2-Tyr}8,00010,000
G40{L-3-NO2-Tyr}5,0006,000
G41{D-3,5-DiNO2-Tyr}8,00010,000
G42{L-3,5-DiNO2-Tyr}8,00010,000

Homo amino acid

Item HHomo amino acid1-9 mg10-19 mg
H1{Har}, HomoArg6,0008,000
H2{Hcy}, HomoCys5,0006,000
H3{HPh}, HomoPhe6,0008,000
H4{D-HPh}, D-HomoPhe6,0008,000
H5{Hse}, HomoSer5,0006,000
H6{D-Hse}, D-HomoSer6,0008,000
H7{HomoCit}, HomoCit6,0008,000
H8{D-HomoCit}, D-HomoCit6,0008,000
H9{HomoLeu}, HomoLeu6,0008,000
H10{HomoPro}, HomoPro6,0008,000
H11{D-HomoPro}, D-HomoPro6,0008,000
H12{beta-HomoIle}, beta-HomoIle10,00012,000
H13{beta-HomoLeu}, beta-HomoLeu10,00012,000
H14{beta-HomoMet}, beta-HomoMet10,00012,000
H15{beta-HomoPro}, beta-HomoPro10,00012,000
H16{beta-HomoVal}, beta-HomoVal10,00012,000
H17{beta-HomoAsp}, beta-HomoAsp19,00023,000
H18{beta-HomoAsn}, beta-HomoAsn19,00023,000
H19{beta-HomoGlu}, beta-HomoGlu19,00023,000
H20{beta-HomoGln}, beta-HomoGln19,00023,000
H21{beta-HomoSer}, beta-HomoSer19,00023,000
H22{beta-HomoThr}, beta-HomoThr19,00023,000
H23{beta-HomoTrp}, beta-HomoTrp19,00023,000
H24{beta-HomoTyr}, beta-HomoTyr19,00023,000

Isotope label

Item IIsotope label1-9 mg10-19 mg
I1N15 Ala16,00023,000
I2N15 Gly16,00023,000
I3N15 Val16,00023,000
I4N15 Pro16,00023,000
I5N15 Leu19,00026,000
I6N15 Ile19,00026,000
I7N15 Phe26,00035,000
I8N15 Asp29,00039,000
I9N15 Thr29,00039,000
I10N15 Glu35,00048,000
I11N15 Lys35,00048,000
I12N15 Tyr35,00048,000
I13N15 Arg64,00090,000
I14N15 Gln64,00090,000

Quenched fluorescent peptide

Item JQuenched fluorescent peptide1-9 mg10-19 mg
J1Abz/ Tyr (3-NO2)15,00017,000
J2Abz5,0006,000
J3Tyr (3-NO2)5,0006,000
J4Glu(EDANS)-NH230,00031,000
J5DABCYL27,00029,000
J6DABCYL/Glu(EDANS)-NH254,00058,000

MAPS and Carrier Complex

Item KMAPS and Carrier Complex1-9 mg10-19 mg
K1Symmetric 2 Branches (Pure)26,00029,000
K1-OrnOrn Symmetric 2 Branches (Pure)31,00035,000
K2Symmetric 4 Branches (Crude)26,00029,000
K2-OrnOrn Symmetric 4 Branches (Crude)31,00035,000
K3Symmetric 8 Branches (Crude)26,00029,000
K3-OrnOrn Symmetric 8 Branches (Crude)31,00035,000
K4Glu 2 Branches (N temrinus)39,00044,000
K5Glycerol 3 branches (C terminus)39,00044,000
K6n-mer Branch peptide on Lys side chain52,00055,000
K7n-mer Branch peptide on Thr side chain62,00066,000
K8n-mer Branch peptide on Ser side chain62,00066,000
K9-AspLys(Asp)39,00043,000
K9-MpaLys(Mpa)39,00043,000
K9-PraLys(Pra)39,00043,000
K10Lys(Maleimide), (middle, C-terminus)58,00064,000
K10N{Lys(Maleimide)}, (N-Terminus)29,00032,000
K11-PalLys(Pal) (middle, C-terminus)39,00043,000
K11N-PalLys(Pal) (N-Terminus)19,00021,000
K11-MaLys(Ma) (middle, C-terminus)39,00043,000
K11N-MaLys(Ma) (N-Terminus)19,00021,000
K12Lys(Alkine) (middle, C-terminus)39,00043,000
K12NLys(Alkine) (N-Terminus)19,00021,000
K13Lys(Suc) (middle, C-terminus)39,00043,000
K13NLys(Suc) (N-Terminus)19,00021,000
K14Lys(methylmalony) (middle, C-terminus)39,00043,000
K14NLys(methylmalony) (N-Terminus)19,00021,000
K15Lys(MTX) (middle, C-terminus)39,00043,000
K15NLys(MTX) (N-terminus)19,00021,000
K16Lys(LA) (middle, C-terminus)39,00043,000
K16NLys(LA) (N-Terminus)19,00021,000
K17Lys(Crotonyl) (middle, C-terminus)39,00043,000
K17NLys(Crotonyl) (N-Terminus)19,00021,000
K18Lys(Cholesteryl) (middle, C-terminus)39,00043,000
K18NLys(Cholesteryl) (N-Terminus)19,00021,000
K19Lys(HYNIC) (middle, C-terminus)39,00043,000
K19NLys(HYNIC) (N-Terminus)19,00021,000
K20Lys(Gama-Glu-Pal) (middle, C-terminus)72,00077,000
K20NLys(Gama-Glu-Pal) (N-terminus)19,00025,000
K21BSA-Peptide N terminus32,00032,000
K21CBSA-Peptide C terminus32,00032,000
K21CysBSA-Peptide Cys35,00039,000
K22KLH-Peptide N terminus32,00035,000
K22CKLH-Peptide C terminus32,00035,000
K22CysKLH-Peptide Cys32,00035,000
K23OVA-Peptide N terminus32,00035,000
K23COVA-Peptide C terminus32,00035,000
K23CysOVA-Peptide Cys32,00035,000

Atom Linker

Item LAtom Linker1-9 mg10-19 mg
L1{Gly}, 2 atoms00
L2{Beta-Ala}, 3 atoms00
L3{GABA}, 4 atoms00
L4{Ava}, 5 atoms6,0007,000
L5{Ahx}, 6 atoms00
L6{Mini-PEG}, AEEA 9 atoms6,0007,000
L7{Mini-PEG2}, AEEEP 13 atoms9,00011,000
L8{Mini-PEG3},AEEEEP 16 atoms12,00014,000
L9{AEA},aminoethoxyacetic acid29,00034,000
L10{PEG6}29,00034,000
L11{PEG11}29,00034,000

Methyl amino acids

Item MMethyl amino acids1-9 mg10-19 mg
M1{Arg(Me)}46,00052,000
M2{ADMA},{Arg(Me)2} asymmetrical46,00052,000
M3{SDMA},{Arg(Me)2} symmetrical62,00070,000
M4{Tyr(Me)}6,0008,000
M5{Thr(Me)}6,0008,000
M6{Ser(Me)}6,0008,000
M7{Cys(Me)}, SMC5,0006,000
M8{Lys(Me)}31,00035,000
M9{Lys(Me2)}15,00017,000
M10{Lys(Me3)}31,00035,000
M11{L-2-Me-Trp}37,00043,000
M12{D-2-Me-Trp}37,00043,000
M13{Tyr(Et)}15,00017,000
M14{D-Tyr(Et)}15,00017,000

N-Methyl amino acid

Item NN-Methyl amino acid1-9 mg10-19 mg
N1{N-Me-Ala}25,00027,000
N2{N-Me-Phe}25,00027,000
N3{N-Me-Leu}25,00027,000
N4{N-Me-Ile}25,00027,000
N5{N-Me-Val}25,00027,000
N6{N-Me-Met}25,00027,000
N7{N-Me-Nle}25,00027,000
N8{N-Me-Nva}25,00027,000
N9{N-Me-Gly}, Sar3,0004,000
N10{N-Me-Ser}50,00054,000
N11{N-Me-Tyr}50,00054,000
N12{N-Me-Thr}50,00054,000
N13{N-Me-Asp}50,00054,000
N14{N-Me-Glu}50,00054,000

Cyclic peptide

Item OCyclic peptide1-9 mg10-19 mg
O1Mono Disulfide bridge26,00029,000
O2Double Disulfide bridge86,00094,000
O3Triple Disulfide bridge344,000384,000
O4Random Triple Disulfide bridge52,00058,000
O5Same Seq. Inter-Disulfide bridge26,00029,000
O6Different Inter-Disulfide bridge52,00058,000
O7Amide cyclic (end)90,00097,000
O8Amide cyclic (Side chain)103,000113,000
O9Thioester cyclic86,00094,000
O10Lactone cyclic86,00094,000

Phosphorylation

Item PPhosphorylation1-9 mg10-19 mg
P1{pSer}15,00017,000
P2{pTyr}15,00017,000
P3{pThr}15,00017,000
P4{D-pSer}46,00052,000
P5{D-pTyr}46,00052,000
P6{D-pThr}46,00052,000
P7Di-sites in sequence46,00052,000
P8Tri-sites in sequence93,000105,000
P94-sites in sequence139,000157,000
P105-sites in sequence186,000209,000

その他・オプション等

Item QOthers1-9 mg10-19 mg
Item QAGMP Clean Room Process107,000
Item QBAliquoting / vial200
Item QCAmino Acid Analysis (AAA)15,000
Item QDN elemental Analysis10,000
Item QESolubility test
Item QFMicrobial analysis
Item QGWater content (Karl Fischer)4,000
Item QHAcetate Content (HIPC)15,000
Item QIMaldi-Tof MS6,000
Item QJEndotoxin analysis12,000
Item QKSwitch saltInquire
Q1Arg(pbf)Inquire
Q2Asp(OtBu)Inquire
Q3Asn(Trt)Inquire
Q4Cys(Trt)Inquire
Q5Glu(OtBu)Inquire
Q6Gln(Trt)Inquire
Q7His(Trt)Inquire
Q8Lys(Boc)Inquire
Q9Ser(tBu)Inquire
Q10Tyr(tBu)Inquire
Q11Thr(tBu)Inquire
Q12Trp(Boc)Inquire
Q13Wang ResinInquire
Q142-CTC ResinInquire
Q15Rink Amide AM resinInquire
Q16Rink Amide MBHA resinInquire


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