Premade Human and Mouse Antibody Libraries

 

HuScL-1(R), HuScL-2(R), HuScL-3(R) and HuScL-4(R) Human Single Chain (scFv) Antibody Library are natural or synthetic libraries of a diversity of over 2.0×109. Recently, we have created a next-generation, fully-human, yeast display scFv library - HuScL-YDP.We also have a HuFabL(R) Human Fab Antibody Library of a size of 2.0×109. Besides human antibody libraries, we have a MuScL(R) Murine Single Chain Antibody Library and a MuFabL(R) Murine Fab Antibody Library

HuScL-1(R): Human Single Chain (scFv) Antibody Library
1. Phagemid phage display system
2. Mono-display by pIX fusion
3. scFv format
4. Construction strategy: VH and VL genes were fully synthesized; mixture of 18 sub-libraries
5. Capacity: 1.35×1010
6. Proliferation in TG1 cells
7. Helper phage: M13K07

http://www.creative-biolabs.org/images/icon_02.gifHuScL-3(R): Human Single Chain (scFv) Antibody Library
1. Phagemid phage display system
2. M13 pIII fusion containing short His6 and V5 detection tags
3. VH-VL format scFv library
4. Collections of human antibody genes from non-immunized donors
5. VL/VH chain recombination through an integrated Cre/lox system
6. Theoretic capacity: 1.0x1016
7. Proliferation in TG1 cells
8. Production of soluble antibody fragments in HB2151
9. Helper phage M13KO7

http://www.creative-biolabs.org/images/icon_02.gifHuScL-4(R): Human Single Chain (scFv) Antibody Library
1. Phagemid phage display system
2. M13 pIII fusion containing short c-Myc detection tag
3. VH-VL format scFv library
4. Seven heavy chain frameworks and seven light chain frameworks representing the structural diversity of human antibody repertoire
5. Complete randomization in "HCDR3" and "LCDR3"
6. Capacity: 1.5x1016

http://www.creative-biolabs.org/images/icon_02.gifHuScL-YDP: Yeast Display Human scFv Antibody Library(New)
1. Yeast display system
2. Fully-human, scFv library for de novo discovery of therapeutically relevant antibodies.
3. Based on 2 liter of blood from approximately 20 donors
4. Based on UltraffTM Yeast Display Technology, can be screened with flow cytometric or magnetic bead based methods
5. Capacity: 1.5x109

http://www.creative-biolabs.org/images/icon_02.gifHuFabL(R): Human Fab Antibody Library
1. Phagemid phage display system
2. M13 gIII fusion containing short His6 and c-Myc detection tag
3. Fab format
4. Collections of human antibody genes from non-immunized donors
5. 2.0x109
6. Proliferation in XL1-blue cells
7. Production of soluble antibody fragments in TOP10F'
8. Helper phage VCSM13

http://www.creative-biolabs.org/images/icon_02.gifMuScL(R): Murine Single Chain Antibody Library
1. Phagemid phage display system
2. M13 pIII fusion
3. scFv format
4. Collections of antibody genes from none immunized mice
5. Capacity: 8.0×108

http://www.creative-biolabs.org/images/icon_02.gifMuFabL(R): Murine Fab Antibody Library
1. Phagemid phage display system
2. M13 gIII fusion
3. Fab format
4. Collections of antibody genes from naive mice
5. Capacity: 6.0x109

                                                                                                     

 

                                                      Premade Antibody & Peptide Libraries

Creative Biolabs has created a series of libraries for de novo discovery of therapeutically relevant antibodies and peptides.

Our pre-made and ready-for-use libraries can accelerate your research and best ensure your success.

To fulfill customers' demands, we provide libraries in the form of scFv, Fab VHH and peptide, original from human, mouse,

rabbit, chicken, camel and llama, or DNA synthesis. If none of the pre-made library meets your requirement,

you are welcome to contact us, and we will be more than happy to create a custom library for you.

These antibody and peptide libraries in both yeast display and phage display formats are available for licensing.

                                         


                                                                                                                                       

 

Libraries

Display Technology

Library Format

Species

Library Size

         Price (¥)

HuScL-YDP

Yeast Display

scFv

Human

1.0x109

 

HuScL-1(R)

Phage Display

scFv

Human

1.35x1010

  *1,600,000

HuScL-2(R)

Phage Display

scFv

Human

1.42x109

  * 1,600,000

HuScL-3(R)

Phage Display

scFv

Human

1.0x1016

  *1,600,000

HuScL-4(R)

Phage Display

scFv

Human

1.5x1016

  * 1,600,000

HuFabL(R)

Phage Display

Fab

Human

2.0x109

   *1,600,000

MuScL(R)

Phage Display

scFv

Mouse

8.0x108

  *1,100,000

MuFabL(R)

Phage Display

Fab

Mouse

6.0x109

   *1,100,000

RaFabL

Phage Display

Fab

Rabbit

7.5x109

 

Chicken-SCL

Phage Display

scFv

Chicken

1.2x109

 

CaVHHL

Phage Display

VHH

Camel

1.5x109

 

LlaVHHL

Phage Display

VHH

Llama

1.5x109

 

TriCo-16

Phage Display

Peptide(16mer)

N/A

2.60x1010

 

TriCo-20

Phage Display

Peptide (20mer)

N/A

1.70x109

 

TriCo-10

Phage Display

Peptide (10mer)

N/A

1.20x109

 

*製品のみの参考価格です。為替変動に対応した柔軟な価格を設定します、ライセンスが必要な使用目的がありますので必ず見積もりをお求めください。。

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株式会社 バイオロジカ
名古屋市中区大須4−10−40
052-262-6732, biologic@rr.iij4u.or.jp
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